"The Eye as a Window of the Brain"
Overall concept underpinning the RECOGNISED project
The general concept of this project is based on the notion that the retina can be used as a window to the brain due to their common embryologic origin. Therefore, the study of the retina in T2D patients in this project will be useful to identify not only those patients at risk of developing dementia, but also different phenotypes with diverse degrees of cognitive decline in terms of velocity and severity. In addition, the study of the common pathogenic pathways involved in the neurodegenerative processes that occurs in the brain and the retina will open up a new research area with clear therapeutic implications.